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Page 1
Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
Nat Metab. 2020 Nov;2(11):1248-1264. doi: 10.1038/s42255-020-00288-1. Epub 2020 Oct 26.
Nat Metab. 2020.
PMID: 33106689
Free PMC article.
Large1 gene transfer in older myd mice with severe muscular dystrophy restores muscle function and greatly improves survival.
Yonekawa T, Rauckhorst AJ, El-Hattab S, Cuellar MA, Venzke D, Anderson ME, Okuma H, Pewa AD, Taylor EB, Campbell KP.
Yonekawa T, et al. Among authors: pewa ad.
Sci Adv. 2022 May 27;8(21):eabn0379. doi: 10.1126/sciadv.abn0379. Epub 2022 May 25.
Sci Adv. 2022.
PMID: 35613260
Free PMC article.
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Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness.
Sharma A, Oonthonpan L, Sheldon RD, Rauckhorst AJ, Zhu Z, Tompkins SC, Cho K, Grzesik WJ, Gray LR, Scerbo DA, Pewa AD, Cushing EM, Dyle MC, Cox JE, Adams C, Davies BS, Shields RK, Norris AW, Patti G, Zingman LV, Taylor EB.
Sharma A, et al. Among authors: pewa ad.
Elife. 2019 Jul 18;8:e45873. doi: 10.7554/eLife.45873.
Elife. 2019.
PMID: 31305240
Free PMC article.
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Publisher Correction: Mitochondrial pyruvate carriers are required for myocardial stress adaptation.
Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED.
Zhang Y, et al. Among authors: pewa ad.
Nat Metab. 2020 Dec;2(12):1498. doi: 10.1038/s42255-020-00322-2.
Nat Metab. 2020.
PMID: 33208925
No abstract available.
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Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis.
Tompkins SC, Sheldon RD, Rauckhorst AJ, Noterman MF, Solst SR, Buchanan JL, Mapuskar KA, Pewa AD, Gray LR, Oonthonpan L, Sharma A, Scerbo DA, Dupuy AJ, Spitz DR, Taylor EB.
Tompkins SC, et al. Among authors: pewa ad.
Cell Rep. 2019 Sep 3;28(10):2608-2619.e6. doi: 10.1016/j.celrep.2019.07.098.
Cell Rep. 2019.
PMID: 31484072
Free PMC article.
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The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity.
Rauckhorst AJ, Gray LR, Sheldon RD, Fu X, Pewa AD, Feddersen CR, Dupuy AJ, Gibson-Corley KN, Cox JE, Burgess SC, Taylor EB.
Rauckhorst AJ, et al. Among authors: pewa ad.
Mol Metab. 2017 Nov;6(11):1468-1479. doi: 10.1016/j.molmet.2017.09.002. Epub 2017 Sep 18.
Mol Metab. 2017.
PMID: 29107293
Free PMC article.
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Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis.
Gray LR, Sultana MR, Rauckhorst AJ, Oonthonpan L, Tompkins SC, Sharma A, Fu X, Miao R, Pewa AD, Brown KS, Lane EE, Dohlman A, Zepeda-Orozco D, Xie J, Rutter J, Norris AW, Cox JE, Burgess SC, Potthoff MJ, Taylor EB.
Gray LR, et al. Among authors: pewa ad.
Cell Metab. 2015 Oct 6;22(4):669-81. doi: 10.1016/j.cmet.2015.07.027. Epub 2015 Sep 3.
Cell Metab. 2015.
PMID: 26344103
Free PMC article.
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